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New genetic markers for Alzheimer's disease uncovered

By: Brandon Heartford

The irreversible affliction that is Alzheimer's sickness afflicts over 5.4 million people. Scientists have gone to great lengths to understand how the disease ravages the brain, typically approaching from the angle of genetics. According to Time, it is genetics that has opened a new avenue of discovery. When it comes to late-onset Alzheimer's - probably the most common form of the sickness - the genes MS4A, CD2AP, CD33, EPHA1 and ABCA7 definitely play a role. Resource for this article - Five new Alzheimer's genes discovered by Newsytype.com.

Genes for Alzheimer are discovered

On April 10, a study could be published in the journal Nature Genetics on Alzheimer's sickness which had 54,000 subjects. There were 44 colleges and research institutes involved in the study with scientists. Scientists discovered five new genetic links in them. It was discovered that it could be easier to get the disease with cholesterol, inflammation and cell transport systems. Other things in the study were shown to possibly help the disease as well as treatments. Thing suggested were behavioral changes and therapies.

Early or onset

The disconnection, and death sometimes, of neurons in the brain is caused by Alzheimer's disease which has the formation of amyloidal plaques and neurfibrillary tangles. There are two types of the disease, early-onset and late-onset. The chances of getting early-onset AD from a parent is at 50 percent. It is very rare to get it at all though since patents ages 30 to 60 only get it 5 percent of the time. There are different gene mutations in the early-onset than there is in the late-onset which develops after age 60.

Moving on

Knowing the brand new Alzheimer's genes can be very beneficial. Still, Jennifer Williamson at Columbia University isn't convinced. The brand new Alzheimer's medicine won't be accessible for a while nevertheless.

"We take pains to be very honest with participants in our trials," she says. "A lot of my job is explaining to people the limitations of what we understand and what we don't understand, and that there are a lot of incremental steps toward having a better understanding of this disease."


Want to know more? The Alzheimer's Disease Education and Referral Center is a good place to go. The web link is easy to discover. It is posted below.

Alzheimer's Disease Education and Referral (ADEAR) Center
P.O. Box 8250
Silver Spring, MD 20907-8250
800-438-4380 (toll-free)


Information from

Alzheimer's Disease Education and Referral Center
nia.nih.gov/Alzheimers

MSN Health
health.msn.com/health-topics/alzheimers-disease/articlepage.aspx?cp-documentid=100271149

National Institute on Aging
1.usa.gov/geeeYj

Time
healthland.time.com/2011/04/05/new-alzheimers-genes-why-they-matter-even-if-they-dont-change-patient-care/

Mayo Clinic discusses discovery of Alzheimer's genes
youtube.com/watch?v=yA6jCROmaoo

Article Source: http://www.articlecontentprovider.com/articlesubmit

Alzheimer's sickness currently devastates the lives of over 5.4 million individuals.

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